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Serine (S) and threonine (T) were replaced with alanine (A) at S2056 and T2609 supply up sites. 2. V3-KC23 mutant carries a frame-shift at position of amino acid 3715 that results in truncation of the protein after 10 amino acids and loss of the thorough PI3K kinase domain. 3. In V3-KD51 mutant aspartic acid (D) at 3921 is replaced with asparagine (N). 4. N: Normal; S: Slightly sensitive; SS, Sensitive; SSS: Very sensitive. Open in a other window Figure 2 The F2Pal 10 pepducin is a where to buy super p-force (100-60 mg) in canada partial agonist in triggering superoxide rescue from human neutrophils.
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